Rattlesnake venom effective against cancer

A substance extracted from rattlesnake venom could raise survival hopes among patients with skin cancer, according to experiments performed by Brasilian researchers. Chromatin, a protein isolated from the venom of the South American snake, increased the survival rate of rats with skin cancer by up to 70 per cent, the Butantan Institute reported.

The protein also helped to significantly retard the development of tumours and even to completely inhibit their formation, according to Butantan, an institute linked to the health department of Sao Paulo state. The researchers heading the unprecedented study discovered that the protein is able to kill cells but its toxic action is exclusively limited to melanoma cells, meaning that it does not affect an organism's other cells. The substance also remains inside a cancerous tumour for only about 24 hours. Researchers admit that they still need to perform other tests on animals and, ultimately, humans before they can think about the possibility of developing a new drug.

The priority, however, before experimenting with it on humans, is to be able to synthesise the protein, that is to produce it in the laboratory without having to extract and process actual snake venom.


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